Elevated Globulin Dogs. In order to better understand the meaning of elevated alkaline phosphatase, it helps gaining a deeper insight into what alkaline phosphatase is and. A high globulin level in a dog's blood work indicates that his immune system is working overtime, potentially battling infection or inflammation.
When only a single type of globulin is responsible for the increase, it is called a monoclonal increase (mono = one; Test interpretation increased globulin concentration (hyperglobulinemia) increases in total globulins can result from increases in any or all of the fractions as determined by electrophoresis. A high globulin level in a dog's blood work indicates that his immune system is working overtime, potentially battling infection or inflammation.